In recent years, the incidence of pseudorabies has no obvious seasonality, and the incidence rate has increased. It has become the second largest infectious disease that harms the reproductive performance of sows in addition to blue ear disease. The disease causes sow reproductive failure is easily ignored by clinical diagnosis, delaying treatment, seriously affecting the economic benefits of the farm. Therefore, the diagnosis and prevention of pseudorabies is of great significance to improve the performance of pigs and the survival rate of piglets. After reviewing a lot of information, the author sorted out the following diagnostic points and prevention measures for pseudorabies, and hoped to provide relevant technical references for the majority of farmers.
Clinical diagnosis points:
1. Sow: The clinical symptoms are not obvious.
(1) cause sows to be stubborn and not estrus.
(2) causing abortion of sows. Abortion caused by pseudorabies occurs in all stages of sow pregnancy, but it is most common in pre-pregnancy and mid-pregnancy, and most of them are mummies and stillbirths.
2, piglets: mainly harm 3-7 days old newborn piglets, can be described as "nine deaths a lifetime." Most of the patients showed elevated body temperature and neurological symptoms such as head tilt, mouth spit, and limb movement. The limbs are soft and weak, more common in the hind limbs, swollen eyelids, and yellow-yellow feces (ineffective with antibiotics).
Figure 1: Pseudorabies suffers from porcine neurological symptoms and limbs open
Figure 2: Pseudorabies suffering from porcine neurological symptoms hind limb paralysis
3. Nursery pigs: a small number occurs and the mortality rate is low. The main manifestations of neurological symptoms, swine head.
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Second, necropsy lesions:
The anatomical pathological changes of the affected piglets are:
(1) The liver and spleen have necrotic spots of yellow-white tip size.
(2) Meningeal bleeding.
(3) The small hemorrhage of the kidney has no obvious change in its shape. Hog chops showed that the newborn piglets had not only small punctiform hemorrhage, but also uneven kidneys. Differential diagnosis in piglets.
Figure 3: Pseudorabies Bleeding point of the needle tip size of the kidney
(4) tonsil hemorrhage and necrosis. Hog may also cause tonsil hemorrhage and necrosis, but the area of ​​hemorrhagic necrosis is significantly larger than that of pseudorabies.
Figure 4: Pseudorabies Bleeding necrosis
Third, prevention and treatment:
According to the pig farm pseudorabies purification system program implemented in our laboratory, combined with the clinical application effect, we recommend the use of genetic engineering seedlings to prevent and control pseudorabies hazards, and gradually realize the purification of pseudorabies in pig farms.
1. Boar: Immunize 3-4 times a year. The dosage is: 1 part of imported seedlings; 2 parts of domestically produced seedlings; for lyophilized vaccine, it should be diluted with special dilution solution.
2, sow: the previous immunization and immunization once every 20-30 days before delivery. The dose is the same as the boar.
3, piglets: first 1-3 days of age with live seedlings nose, and drop two nostrils, the dose is 0.5-1. The second time is 5-7 weeks old and the first part is intramuscular.
If pseudorabies is found, it can be immunized with a vaccine. If the piglet has a hair disease, the whole nest is immunized with live vaccine, and the dose is 1-1.5. The sow is 2 servings. Combined with the incidence of pigs, take appropriate symptomatic treatment.
The large-scale pig farm should be immune to the pseudorabies vaccine. With the favorable conditions of the diagnostic room, the purification of the pseudorabies disease in the farm can be gradually realized. In addition, it is necessary to grasp the rodent control work of the pig farm and eliminate the storage and spread of the pseudorabies virus. Drugs should be tested on the farm every 2-3 months. Rodenticides can be used to select rodent fans who are less harmful to pigs. Avoid toxic fluoroacetamide or sodium fluoroacetate.
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